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Via the incretin pathway, they stimulate insulin release, suppress glucagon release, slow down gastric emptying, and enhance central satiety signal
Contraindicated in patients with personal or family history of medullary thyroid carcinoma (MTC) or Multiple Endocrine Neoplasia syndrome type 2 (MEN 2)
00:12:45 Vickie Danaher Patients on simvastatin should also not take more than 20 milligrams once daily of this cholesterol medication if also taking orforglipron
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