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For instance, GLP-1 treatment can be expensive, and insurance coverage may be limited
8.3 Buccal/sublingual delivery Buccal and sublingual delivery avoids GI degradation and partially avoids first-pass hepatic metabolism (venous drainage from these regions partially bypasses the portal circulation)
Adams Collins, a nutrition expert at the U.K.'s University of Surrey, says the injections mimic a natural hormone called GLP-1, which regulates hunger, per the BBC
Current recommendations from the American Society of Anesthesiologists (ASA) suggest withholding GLP-1 agonists one week prior to the procedure for those on weekly dosing and withholding GLP-1 agonists on the day of the procedure (American Society of Anesthesiologists 2024)
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