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The promise and peril of GLP-1 agonists: What we do (and don't) know as of August 2024 Yulan Egan Aug 21, 2024 6 min read Across the past two years, GLP-1 agonistsa class of drugs that treat type 2 diabetes (T2D) and obesityhave not only become a major source of industry discourse, but a household name

[23] NICE guidance emphasises that GLP-1 medications should be combined with lifestyle modifications, including dietary changes and increased physical activity, to optimise outcomes

Headaches rank among the most commonly reported side effects during the first weeks of GLP-1 therapy, affecting roughly 1015% of patients in clinical trials

This is more commonly associated with oral supplementation at higher doses but can theoretically occur with any route of administration