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Often prescribed under brand names including Ozempic and Wegovy, it can help produce more insulin, which reduces blood sugar and therefore helps control type 2 diabetes

Two techniques are being used to measure endothelium-dependent vasodilation

The pattern of results, particularly the amplification of benefit at higher weight loss thresholds, is consistent with the hypothesis that HRT restores a metabolic environment that makes GLP-1 therapy more effective: improving insulin sensitivity, preserving lean mass, reducing the inflammatory burden that blunts metabolic responsiveness, and supporting the mitochondrial function that underlies energy regulation

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