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GLP-1 agonists are medications that mimic the effect of this hormone and, on average, lower hemoglobin A1C by 0.8% to 1.5%

Semaglutide is most successful when incorporated into a holistic approach that includes a balanced diet, exercise, and healthy lifestyle habits

Legal and Ethical Considerations: While off-label use of medications is legal and sometimes necessary, healthcare professionals and experts must carefully evaluate the risks and benefits before prescribing medications off-label

Patients, charities and health officials have called for prescribers to stop issuing a diabetes drug for weight loss amid a national shortage for those most in need