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It is well known that gastric and intestinal lesions develop by the inhibition of either COX-1 and COX-2 activity by COX-inhibitors (Halter et al
Ultimately, these combined molecular and morphological alterations cause pathological displacement or closure of the implantation window, preventing embryos from achieving normal positioning and adhesion within the endometrium
1991 Oct 26;303(6809):1026-9
Meta-analyses on GLP-1 receptor agonists and fracture occurrence have yielded conflicting results, possibly due to short study durations and fractures not being primary outcomes
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