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On one hand, metabolites of glycyrrhizin enhance vascular contraction in response to pressor hormones such as angiotensin II, thereby increasing vascular tension

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These may occur if: The injection was too shallow or too deep The fluid volume was too high for the site The product was too concentrated or acidic Local immune cells formed a small granuloma (harmless but annoying) Applying a warm compress can help disperse the fluid and reduce the lump

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Subsequently, the released ferrous/iron ions will react with excess hydrogen peroxide in the cell to produce a Fenton-like reaction generating hydroxyl free radicals (OH), and induce ferroptosis of tumor cells [205]

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10.1158/0008-5472.Can-20-1488 158 WangY.ZhaoG.CondelloS.HuangH.CardenasH.TannerE

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