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In the central nervous system, agents like exedin-4 and liraglutide reduce neuroinflammation by inhibiting microglial activation and cytokine production (IL-1, IL-6, TNF- ), while preserving neuronal integrity and preventing cognitive dysfunction associated with sepsis
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Wegovy single-dose pens should be stored refrigerated but may be kept at temperatures up to 86F (30C) for up to 28 days prior to use, then discarded after injection
Figure 5 A meta-analysis of clinical studies indicated that treatment with GLP-1RAs of obese patients with T2MD did not increase the risk of breast tumors, nor did it increase the risk of acute pancreatitis, pancreatic cancer, and overall tumor neoplasia (207209)
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