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The APRIL study: A randomised, controlled crossover study

Fleur's concept addresses the limitations of current therapies through a biomimetic strategy that leverages the body's natural GLP-1 production mechanisms: Utilize a probiotic oral delivery system to populate the gut microbiome long-term with natural (short-lasting) GLP-1 producing bacteria

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Potentially Higher Long-Term Costs From a fiscal responsibility perspective, the growth of these programs (from $886 million in 2019 to nearly $2.7 billion in 2025) deserves scrutiny