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By infusing fillers straightforwardly into the scar tissue, dermatologists can briefly streamline the skin's surface and improve its appearance
To understand the underlying mechanisms, inhibitors targeting the Notch pathway (DAPT) and NF-B pathway (BMS) were also applied to HUVEC and murine CLI models
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They rewire substrate use, biosynthesis, redox state, mitochondrial quality control, amino acid handling, ketone adaptation, epigenetic regulation, inflammation, and inter-organ communication
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