Medications make more sense for people with significant weight to lose for health reasons, those with type 2 diabetes or prediabetes where GLP-1 receptor agonists address both conditions simultaneously, individuals who have tried lifestyle changes and supplements without adequate results, and anyone whose healthcare provider recommends pharmaceutical intervention based on risk assessment
Wild yam extract (vegan phytomucin) In a review from 2023, the authors noted that a compound in wild yams called gracillin may help reduce skin inflammation and, in a mouse study, significantly improved the skin barrier and hydration status of subjects with atopic dermatitis.10 Wild yams also appear to have antimicrobial capabilities, which has led to their use in traditional medicine as a treatment for skin infections, among other things (e.g., cough, menstrual pain, swelling, stomach upset).11 GHK-Cu One of the many potential benefits of topical GHK-Cu is increased skin hydration
The 3.0-mg dose (approved for treatment in obese subjects) was associated with a further 1-bpm HR increase over 24 h compared with the 1.8-mg dose
Per FDA Retatrutide and cagrilintide cannot be used in compounding under federal law
