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Generation of human dendritic cells that simultaneously secrete IL-12 and have migratory capacity by adenoviral gene transfer of hCD40L in combination with IFN-
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In THP1 cells from rheumatoid arthritis patients, LPS stimulation increases H3 and H4 acetylation at the CCL2 promoter, which can be reversed by TNF- inhibitors such as etanercept and adalimumab (77)
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