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The clinical evidence exists but is limited small trials, older studies, no large RCTs
BER loaded nanoformulations directed for intranasal administration have been previously reported in several studies
The most commonly used treatments for skin whitening are: Topical creams: Topical creams containing ingredients such as hydroquinone, kojic acid, or arbutin are commonly used for skin whitening
Healthcare providers should ensure appropriate documentation, informed consent, and risk mitigation strategies
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