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STEP-1 showed 39% of semaglutide weight loss was lean mass

SURPASS-2 pitted tirzepatide (5mg, 10mg, and 15mg/weekly) against semaglutide (1mg/weekly) and directly compared their effectiveness for T2D management in almost 2000 study volunteers for 40 weeks [22]

The difference in redox metabolism between these two ASD groups is further supported by the fact that the relationship between a measure of chronic oxidative damage, notably plasma 3NT, and many of the indices of development, language and behavior were different between the two groups