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How GLP-1 drugs reduce cravings in people with addiction is not well understood, but the authors of the new paper offer one possibility

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Pregnant or breastfeeding women should avoid both compounds

Although butyrate has been proposed to serve as an energy substrate via -oxidation, the specific mechanisms by which microbial metabolites repair diabetes-associated mitochondrial damage and bridge energy supply-hormone secretion remained undefined (Tan et al., 2014