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Nausea and vomiting are likely to occur, and the gag reflex will be impaired, which could cause choking or aspirating on vomit

45 Accordingly, compensatory reductions in energy expenditure in PF mice, but not in SEMA-treated mice, may underlie the differences in EAT volume and body weight observed after 4 weeks of treatment

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Mental health improvements are typically observed alongside other health benefits and should be monitored by a healthcare provider as part of comprehensive care