not losing weight on 7.5 tirzepatide 10 Reasons Why You're Peptides & GLP-1s (Fix This) Tirzepatide - no weight loss

The side effect profile is more serious than GLP1R agonists , including depression and suicidal ideation and it is not approved for other types of obesity

Glucagon-like peptide-1 (GLP-1) is a glucoregulatory hormone synthetized in the intestines and the brain, involved in the maintenance of energy homeostasis mainly by stimulating insulin secretion and regulation of appetite

Therefore, because neurotransmitter imbalance contributes to depressive behaviors in patients with depression as described above, the appropriate modulation of neurotransmitters in the brain is key to treating depression ( Figure 2 )

There are some conditions which make patients straight out ineligible for tirzepatide therapy