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Mechanistically, GLP-1R activation alleviates OA by fostering chondrocyte anabolic metabolism while inhibiting catabolism, safeguarding chondrocytes from endoplasmic reticulum stress and apoptosis, and displaying anti-inflammatory and antioxidant properties [15,16,17]

"Rhodiola rosea in stress induced fatiguea double blind cross-over study of a standardized extract SHR-5 with a repeated low-dose regimen on the mental performance of healthy physicians during night duty." Phytomedicine 7.5 (2000): 365-371

Effect of aldose reductase inhibitors on naphthalene cataract formation in the rat

Advances in precision medicine could allow clinicians to tailor therapies based on genetic and metabolic profiles