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Pellets: Small testosterone pellets are surgically implanted into the hip or abdomen and slowly release testosterone over several months before needing replacement
Approximately 25% of total weight lost on tirzepatide was lean mass (SURMOUNT-1 DXA substudy), and in semaglutide trials, that proportion may reach up to 40% (STEP 1 DXA subset)
While both target similar mechanisms to aid weight loss, semaglutides extended-release formulation leads to more sustained effects and greater overall weight reduction
, IL-6 and high-sensitivity CRP, 6)
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