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Staresinic, M., Petrovic, I., Plestina, S., Perovic, D., Rucman, R., Turkovic, B., & Sikiric, P
Findings include: Accelerated wound closure rates in multiple animal models Enhanced re-epithelialization and granulation tissue formation Improved collagen deposition and organization in healing wounds Reduced scar formation and improved cosmetic outcomes GHK-Cu specifically demonstrated increases in skin thickness, elasticity, and firmness in controlled studies, while BPC-157 showed protective effects against various skin damage models
In a formal review, the agency concluded that BPC-157: Lacks sufficient safety data and has not been shown to be safe or effective in humans FDA Compounding Memorandum, 2023 The FDA also lists BPC-157 as ineligible for 503B compounding , which prohibits it from being added to compounded medications by outsourcing facilities