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EGCG induces autophagy by targeting the PI3K-AKT-mTOR pathway, and also inhibits H2O2-induced activation of glycolysis in endothelial cells, maintaining mitochondrial function and reduces ROS production [73].These studies suggest that tea polyphenols not only scavenge oxidative damage products through autophagy, but also reduce the source of ROS generation by inhibiting aberrant metabolic pathways
S.van GroenT.et al (2010)
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Effect of Glutathione Infusion on Leg Arterial Circulation, Cutaneous Microcirculation, and Pain-Free Walking Distance in Patients With Peripheral Obstructive Arterial Disease: A Randomized, Double-Blind, Placebo-Controlled Trial 23
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