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That means fertility may increase, sometimes unexpectedly, and women should be counseled regarding this. To prevent pregnancy you should use reliable birth control while taking GLP-1s, she says

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Patients with: Personal or family history of Medullary thyroid cancer MEN2 syndrome Severe gastroparesis Pregnancy/ breastfeeding Pancreatitis or breastfeeding Severe depression Eating disorders Liver or kidney disease (caution advised) Why GLP-1 and Inflammation and Arthritis Matter We now understand that GLP-1 medications are not just weight loss drugs. They are anti-inflammatory, immune-modulating, metabolic medications that can dramatically shift health outcomes for patients with arthritis and autoimmune diseases

That complexity fuels interest in therapies that modulate multiple pathways