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In refractory cases characterised by persistent azoospermia, assisted reproductive techniquesincluding testicular sperm extraction (TESE) and intracytoplasmic sperm injection (ICSI)may enable conception, although success depends on residual spermatogenic capacity (80)
NICE guidance now recommends early consideration of SGLT2 inhibitors for people with established cardiovascular disease, heart failure, or chronic kidney disease
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34 In patients with plaque psoriasis treated with liraglutide, iNKT cells in psoriatic plaques decreased while circulating iNKT cells increased, likely because of the immunoregulatory action of GLP-1 on iNKT cells
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