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Automated Systemic Amino Acid Scanning: An automated in-silico alanine scanning approach, named "Modigy" (a combination of Modeller and Prodigy), was performed on the peptide backbone of semaglutide

STAT3 a key oncogene with dual functions of signal transduction and transcriptional activation, which is hyperactivated in the formation of most human cancers and plays a critical role in cell proliferation, angiogenesis, metastasis, and immunosuppression (El-Tanani et al., 2022)

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