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EXE-HIP was prepared with sodium docusate (1:4 molar ratio), increasing lipophilicity (log P = -2.9 0.3 vs 0.9 0.2 for EXE) and markedly improving solubility in lipid excipients, especially in Labrafac MC60, a known promoter of intestinal permeability

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Conclusions In conclusion, GLP-1-RAs present a safe, effective and well-tolerated treatment option for achieving significant weight loss in pwIIH, leading to headache improvement after six months as well