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Because many previous reports demonstrated that hypertension alone induces a shift from fatty acid oxidation toward increased glucose utilization in cardiac muscle, hypertension complicated with HFpEF might have additive effects on energy metabolic failure in heart
Preclinical and observational data suggest that side effects primarily depend on dosage, frequency, and individual metabolic response
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Ensuring adequate protein intake significantly reduces this side effect, which connects to our nutrition section below
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