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Increased blood glucose concentration induces an increase in the production of a polypeptide hormone called insulin (90, 91)

510% of the ER-negative breast cancers have also shown sensitivity to tamoxifen treatment via ER independent signaling pathways [17, 18]

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Your healthcare provider can perform appropriate monitoring, including HbA1c testing (at least twice yearly if stable and at goal, or quarterly if therapy has changed or targets are not met), fasting glucose measurements, weight tracking, and assessment of cardiovascular risk factors