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Gastrointestinal adverse events were the most commonly reported and were more frequent during dose escalation
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Unfortunately La Barre's idea was largely forgotten over the next three decades
The novel fixed-dose combination Cagrilintide-Semaglutide (CagriSema), merging a GLP-1 receptor agonist (Semaglutide) with an amylin analog (Cagrilintide), represents a significant therapeutic advance
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