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For patients with a history of treated and stable malignancies, tesamorelin therapy should be initiated only after careful evaluation of the potential benefit of treatment relative to the risk of re-activation of the underlying malignancy

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1 Red blood cell analyses showed that SOD activity and malondialdehyde (MDA) levels were significantly elevated and positively correlated with disease extent and activity, while CAT and glucose-6-phosphate dehydrogenase (G6PD) activities were significantly reducedfindings the authors described as supporting the hypothesis that widespread enzymatic deficiencies underpin vitiligo pathogenesis

1113 Nearly all trials are conducted over shorter durations of time and there is no long-term data available on the effect of orally administered glutathione on skin pigmentation