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Both modifications sit in the region that IGF binding proteins recognise, and the functional consequence is a large loss of IGFBP affinity while type 1 IGF receptor binding is largely preserved
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Conclusion This study identifies distinct expression patterns and functional effects of GLP-1 and GIP in jejunal muscle from obese individuals with and without T2DM
In mouse models and autopsy analysis of AD patients, mitochondrial dysfunction and increased reactive oxygen species enhance A aggregation
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