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If large swathes of the general public start taking them off-label for weight loss and then we find out years later that there are bad side effects, it could be a real issue. Rethinking long-term weight management strategies to overcome cost barriers Yet another dimension affecting the use of GLP-1RAs is cost

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Participants also reported visible improvements in skin tone and texture, with no irritation or adverse effects

In contrast, T2DM may be associated with chronic oxidative stress, exacerbated by dyslipidemia and hypertension, which increase retinal 8-hydroxydeoxyguanosine (8-OHdG), a marker of DNA oxidative damage (63)