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Because of this, certain groups may want to exercise caution or avoid these supplements altogether: People taking hormone-related or other prescription medications Ingredients in hormone-support supplements may interact with treatments such as hormone replacement therapy (HRT), birth control, diabetes medications, thyroid hormones, immunosuppressants, antihypertensives, sedatives, and others.35 These interactions can alter how medications work or increase the risk of side effects

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Higher doses of vitamin B 12 supplements are recommended for patients taking medications that interfere with its absorption (see Drug interactions)