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Most GLP-1 medications share similar side effect profiles, with gastrointestinal issues being most common
But, what are compounded GLP-1s, anyway
In a 2025 observational cohort, the Risk of Vestibular Disorders with Semaglutide and Tirzepatide study reported dizziness in 18% of semaglutide users compared with 10% in the control group, indicating a higher-than-baseline incidence and reinforcing the need to monitor for dose- or timing-related patterns
According to the MHRA-approved Summary of Product Characteristics (SmPC), the most frequent side effects include nausea (reported in 43.9% of patients), diarrhoea (29.7%), vomiting (24.5%), constipation (24.2%), and abdominal pain (27.2%)
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