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The investigational therapy demonstrated significant reductions in HbA1c levels, outperforming placebo and active comparators, and contributed to meaningful weight loss in patients inadequately controlled on standard treatments

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Using these enzyme preparations with a defined GSH concentration (20 M) in the established two-step in vitro reactions, we found that the extent of conversion of the ultrafiltered flavan-3,3,4-triol ( 4 ) depended on the applied concentration of the purified Pt GSTF8, confirming that this enzyme is required and sufficient for the observed conversion to cyanidin (Extended Data Fig

"Stick with the FDA-approved versions of prescription medications rather than substitutes or compounded versions," he advised