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Currently Approved GLP-1 Drugs Novo Nordisk: Semaglutide (Ozempic/Wegovy/Rybelsus) Semaglutide differs chemically from GLP-1 only slightly, yet this small difference allows semaglutide to have a half-life of around 7 days in the blood, making it a longer-lasting GLP-1

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IGlarLixi is a fixed-ratio combination of insulin glargine and lixisenatide, containing 100 U/mL of glargine and 33 lg/mL of lixisenatide in a 3-mL prefilled injection pen

For body-composition goals (lean mass gain, fat loss), a mid-range dose may be more effective