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The majority of peptide therapies are delivered through an IV or by subcutaneous injections, rather than by oral supplements

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In addition to these widely used AOMs, Exenatide, one of the earliest GLP-1 RAs approved by the FDA and EMA for T2DM management, is not indicated for weight management but remains clinically relevant, particularly in older adults with comorbid obesity and T2DM, given its long-term clinical experience and established tolerability profile [26,27,28]

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Pharmacotherapy of type 2 diabetes: an update

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