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United States FDA / DSHEA Lens DSHEA dietary supplement pathway alignment NDI notification risk assessment (novel liposomal systems, unusual carriers, aggressive dose stories) GRAS / established-ingredient status checks where relevant Supplement Facts compliance and structure/function claim boundaries Early ingredient screening reduces NDI exposure and keeps US launch paths DSHEA-defensible

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Study Design 3.4

The safety profile of dual agonists is similar to pure GLP-1 agonists, with the main difference being slightly higher rates of GI side effects