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3 Unlike some other classes of anti-obesity medications (AOMs), GLP-1 RAs influence appetite regulation by delaying stomach emptying and impacting specific brain regions governing food intake
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While the body does produce natural GLP-1, this endogenous hormone is rapidly broken down by the enzyme dipeptidyl peptidase-4 (DPP-4) within minutes of secretion, making it unsuitable as a therapeutic agent without pharmaceutical modification
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