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An example of a hybrid molecule is tirzepatide, which combines the effects of GLP-1 and GIP receptor agonism to maximize the efficacy of two incretins
Cells were first gently lysed with the cytoplasmic extraction buffer to release cytoplasmic components, and the supernatant was collected after centrifugation as the cytoplasmic protein fraction
Khosravi Z, et al
when a significant overall effect was detected, post hoc pairwise comparisons were performed using the MannWhitney U test
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