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We also estimated that oral semaglutide provided patients with +0.23 QALYs and was more cost-effective than lixisenatide, like a study conducted in Sweden proving that semaglutide injection provided greater clinical benefit (+0.71 QALYs) than lixisenatide in patients with poor basal insulin control at a lower cost ( Oral semaglutide demonstrated inferior cost-effectiveness compared to exenatide (ICER: $88,776.61/QALY), possibly due to the latter being the first GLP-1 RA available in the Chinese market, with a lower annual price than other GLP-1 RAs (i.e., semaglutide, dulaglutide, liraglutide, and lixisenatide)
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