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Tirzepatide may offer more significant weight loss and improved glucose control compared to semaglutide, as it targets both GIP and GLP-1 receptors
To bridge these gaps, this review distinguishes itself from prior literature in three key aspects: Firstly, we propose an integrated Gut-Metabolism-Endocrine network model, uniquely positioning gut microbiota dysbiosis as a potential upstream regulator that initiates the systemic OS cascade, rather than merely a secondary symptom
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