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Last reviewed: July 16, 2026 Last updated: July 16, 2026 Written by: Jay Hastings, CEO of PlexusDx Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations
Amgen is advancing a long-acting GLP1 analogue (MariTide), Boehringer Ingelheim and Zealand are developing a GLP1 and glucagon dual agonist (survodutide), and companies like Viking (VK2735), Altimmune (pemvidutide), and others are testing their own GLP1, dual, or oral small-molecule programmes
In my own practice, I see fatigue as the main impairment in my clients, even after thyroid hormone treatment improves their thyroid levels
Body composition changes are visible by week two to four in users who are disciplined with diet and training
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