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Nasca C, Dobbin J, Bigio B, Watson K, de Angelis P, Kautz M, Cochran A, Math AA, Kocsis JH, Lee FS, Murrough JW, McEwen BS, Rasgon N (2021) Insulin receptor substrate in brain-enriched exosomes in subjects with major depression: on the path of creation of biosignatures of central insulin resistance

5Amino-1MQ 5-Amino-1MQ is a small-molecule compound targeting the NNMT pathway, and its currently being studied for its role in cellular metabolism, energy regulation, and adipocyte-related biochemical models

Postprandial glucose levels (measured two hours after eating) decreased by 36%

Here's what to watch for: Respiratory changes: Thinner mucus, less frequent throat clearing, easier breathing during exercise