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Overall, we conclude from these experiments that ROXY9 most likely adopts a canonical thioredoxin fold akin to GRXC2

Also, SOD1 G93A mice show significantly increased protein carbonyl levels in the spinal cord, including elevated carbonylation of mutant SOD1, which has been linked to motor neuron degeneration (Poon et al., 2005)

Human trials and mechanistic studies show improvements in lipids, glycemia, endothelial function, skin aging markers, and body composition