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This poses a large obstacle in the investigation of PPI use as most studies are forced to rely on retrospective studies or non-human models, which further increase the number of variables leading to an unclear illustration of the effect of PPIs
This is not ideal, as we want to preserve muscle or lean mass while we lose weight to avoid complications like sarcopenia and bone loss
Staying Safe While Finding Cheaper Options Cost-reduction efforts for GLP-1 medications must prioritize safety and regulatory compliance
Furthermore, the EMA has withdrawn the weight loss medication rimonabant, a selective cannabinoid type 1 receptor antagonist, due to its reported links to increased risks of depression and suicide [70]
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