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Why take a lower dose of a medication when we know the dose that already works

But a study by Canadian scientists published in Jama Ophthalmology has found that after six months of use GLP-1 RAs are associated with double the risk of older people with diabetes developing neovascular age-related macular degeneration compared with similar patients not taking the drugs

Despite variability across studies, body composition analyses from clinical trials have shown that a relevant proportion of total weight reduction under GLP-1RAs therapy can be attributed to the loss of lean mass, including skeletal muscle [12]

Personal medical history should be discussed with a healthcare provider to assess risk