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Acknowledgments We extend our deepest gratitude to the School of Medicine at Universidad San Francisco de Quito (USFQ), the Instituto de Investigaciones en Biomedicina (USFQ), and the Mito-Act Research Consortium in Quito, Ecuador, for their unwavering support of our research and initiatives.We also wish to express our special thanks to the Instituto de Neurociencias for their invaluable support during Kevin Zambranos Ph.D

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