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22 However, epidemiological and clinical studies have linked hyperuricemia to the development of various conditions, including chronic kidney disease, fatty liver, metabolic syndrome, hypertension, insulin resistance, obesity, type 2 diabetes, and cardiovascular and cerebrovascular disorders

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K.MoselerA.SchwarzlnderM.et al (2019)

This mode of action confirms what the experts have been saying for several years, namely that it is a reduction in calorie intake that remains the main means of losing weight (physical exercise has enormous health benefits, but does not have major effects on weight loss)