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A 2022 systematic review in Growth Hormone & IGF Research identified 47 clinical trials involving Tesamorelin versus 23 for Sermorelin reflecting the significantly higher clinical investment in Tesamorelins metabolic applications
They could be inert, or they could have their own unexpected biological effects, completely confounding your results
This can make trying to compare nootropic supplements confusing at best
There is no universal winner the "better" peptide depends on what a research protocol is trying to model and how an individual responds
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