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In one study, the administration of IGF-1 to rats with diabetic cardiomyopathy produced several beneficial effects, including a reduction in myocardial apoptosis, oxidative stress, inflammation, interstitial fibrosis, and metabolic irregularities
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Other studies have demonstrated a dose-dependent effect of acetyl-l-carnitine in counteracting oxidative stress caused by arsenic and improved mitochondrial function in a rat hippocampus model and reduced the levels of free radicals induced by cuprizone in murine corpus callosum [21, 22]
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